I have a directory C:\Program Files (x86)\Tools where I have various downloaded tools, at the moment it just contains another directory with the tool "GPT fdisk", a command line partition tool:
https://sourceforge.net/projects/gptfdisk/The folder structure is "C:\Program Files (x86)\Tools\gdisk-windows-1.0.9".
Both RogueKiller and Adlica Diag will flag the *directory* "C:\Program Files (x86)\Tools" as possible malware (Adw.TopTools).
It puzzles me why you would flag a directory at all, without analyzing what's in that directory.
I just add "C:\Program Files (x86)\Tools\" to my exclusions, but that also means that if any possible future tools I put in there should contain anything suspicious then RougeKiller/Diag won't even try to catch that.
You might want to look into this.